Yes, Ghana is generally safe for solo female travelers. However, taking common-sense precautions is always advisable, such as avoiding walking alone at night in unfamiliar areas, staying aware of your surroundings, and trusting your instincts. Dressing modestly and respecting local customs can also help minimize unwanted attention. Additionally, consider using reputable transportation services like Yango and accommodations, and inform someone trustworthy about your travel plans.